COAGULOPATHY

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HYPERCOAGULABLE STATE

✿ Coagulation cascade disorders
  ✧ antithrombin deficiency
  ✧ protein c deficiency
  ✧ protein s deficiency
  ✧ factor v leiden
  ✧ prothrombin mutation
  ✧ hypofibrinolysis
  ✧ hyperfibrinogenemia

✿ Platelet disorders
  ✧ thrombocytosis
  ✧ essential thrombocythemia

✿ Systemic diseases
  ✧ liver disease
  ✧ antiphospholipid syndrome
  ✧ malignancy
  ✧ polycythemia vera
  ✧ paroxysmal nocturnal hemoglobinuria
  ✧ multiple myeloma
  ✧ macroglobulinemia
  ✧ inflammatory bowel disease
  ✧ nephrotic syndrome
  ✧ trauma / surgery
  ✧ immobilization
  ✧ pregnancy / contraceptives
  ✧ smoking
  ✧ obesity
HYPOCOAGULABLE STATE

✿ Coagulation cascade disorders
  ✧ coagulation factor deficiency
  ✧ hyperfibrinolysis
  ✧ hypofibrinogenemia
  ✧ vitamin k deficiency
  ✧ anticoagulants
  ✧ thrombolytics

✿ Platelet disorders
  ✧ thrombocytopenia
  ✧ platelet dysfunction
  ✧ von willerbrand disease
  ✧ antiplatelets

✿ Systemic diseases
  ✧ liver disease
  ✧ disseminated intravascular coagulopathy
  ✧ uremia
  ✧ malignancy
  ✧ hypothyroidism
  ✧ systemic lupus erythematosus

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